This study on stress granules (SG)s identified 1,754 consistently enriched proteins, with 74% of the top 50 ranked proteins being true positive SG proteins, underscoring Microscoop’s potential in advancing SG biology and driving therapeutic innovations.
Microscoop® identifies ciliary proteins with high specificity, uncovering critical insights into their structure and function, in a significant advancement in the exploration of ciliary biology and its implications for health and disease.
The Microscoop® identifies low-abundance proteins and overrepresented complexes in nuclear and nucleolar structures, such as the spliceosome and RNA polymerase, with remarkable specificity.
A Microscoop® stress granule study identified 1,754 consistently enriched proteins with 96% specificity among the top 50 ranked, including novel SG-associated proteins, uncovering potential therapeutic targets for stress-related diseases.
Syncell Microscoop® integrates cutting-edge microscopy, photo-biotinylation, and mass spectrometry to enable high-resolution, hypothesis-free protein discovery. The platform identifies and isolates proteins from specific cellular structures, such as nuclei, stress granules, and primary cilia, paving the way for advancements in diagnostics, therapeutic development, and disease research.
