Cancer progression and therapeutic response are governed by spatially restricted protein networks within defined subcellular microenvironments, including signaling complexes, tumor–immune interfaces, and specialized organelles.
Microscoop® enables nanoscopic proteomics guided by microscopy, allowing researchers to precisely capture the proteome of user defined regions of interest in cells and FFPE tumor tissue.
This capability allows scientists to uncover functional regulators of cancer biology that can be translated into patient-relevant outcomes.
Tumor progression and therapeutic response are shaped by interactions between cancer cells and their surrounding microenvironment. These processes are mediated through highly localized interfaces and signaling networks.
Microscoop enables proteomic analysis of tumor–immune contact regions in cells and FFPE tumor tissue, providing insight into molecular mechanisms governing immune responses.
Tumors are composed of diverse cell populations organized across spatial gradients that influence disease progression and treatment response.
Microscoop enables proteomic discovery within microscopy-defined tissue regions, allowing identification of known and novel tumor surface proteins.
Many cancer-driving mechanisms occur within nanoscale cellular structures that regulate signaling, metabolism, and transcription.
Microscoop enables in situ proteomic analysis of precisely defined regions—such as mitochondrial interfaces and fluorescently labeled condensates—allowing researchers to uncover the protein networks that drive these mechanisms.
Connecting mechanistic insights to clinically actionable outcomes requires studying protein networks directly in disease-relevant tissue contexts.
Microscoop enables nanoscopic proteomics within FFPE tumor sections, allowing direct interrogation of protein networks in patient derived tissue with preserved spatial context.
