Advancing Cell Biology with Spatial Proteomics: Unbiased Protein Discovery in Nanoscale Structures
Webinar
Deciphering cellular function requires understanding protein localization and interactions at the subcellular level. Traditional proteomic tools, however, lack the precision to target specific nanoscale regions. The Syncell Microscoop® platform addresses this challenge by integrating high-resolution microscopy (~350 nm) with automated, image-guided protein isolation. Using femtosecond-pulsed, two-photon photo-biotinylation, Microscoop® selectively labels proteins within user-defined regions of interest at sub-organelle resolution.
This enables cell biologists to:
- Unbiased protein discovery — no predefined markers required
- Dynamic biology revealed — capture proteomic changes across cellular states and conditions
- Nanoscale signaling insights — map pathway-specific localization and interactions
In this webinar, we will showcase how Microscoop® maps protein localization and interactions within previously inaccessible subcellular structures—such as stress granules, peridroplet mitochondria, and immune synapse—providing new insights into spatial biology and advancing our ability to connect molecular context with biological function.
Speaker
Ian Ross
Senior Field Application Scientist
Syncell Inc.
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For Research Use Only. Not for use in diagnostic procedures.
